Karbinal ER (carbinoxamine maleate) is an H1 antagonist, a type of antihistamine, used to treat a wide variety of allergic reactions, including seasonal and perennial allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic skin manifestations of urticaria and angioedema, dermatographism, as therapy for anaphylactic reactions, and to improve the severity of алергични реакции към кръв или плазма